Expression of Bone Morphogenetic Protein ( BMP)-2,4 in Mouse Embryonic Tooth During the Bud Stage 骨形成蛋白-2、4在胎鼠牙胚蕾状期的表达
Human tooth development is a consecutive process, which includes bud stage, cap stage, bell stage and tooth root development. 人类牙齿的发育,经历蕾状期、帽状期、钟状期、牙根发育和牙齿萌出期。
In this case the cells were taken from what is known as the tooth germ, the little bud that appears before an animal grows a tooth. 在这一研究中,这些细胞来源于所谓的牙胚即动物出牙前发生的幼芽。
RESULTS: ① There were significantly positive expressive results in situ hybridization in rat tooth germ bud stage. Its expressive parts concentrated mainly outside embryo mesenchyme around tooth germ and the top of tooth bud. 结果:①大鼠牙胚蕾状期原位杂交可见明显阳性表达结果,其表达部位主要集中于牙胚及牙蕾顶部邻近的外胚间充质。
Results c-jun was found negative in the mouse tooth bud and cap stage, but stained positive in the bell stage. 结果c-jun原癌基因在小鼠牙胚的蕾状期、帽状期呈阴性表达,在钟状期牙胚的成牙本质细胞中呈阳性表达。